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Fig. 9 | Model for <t>the</t> <t>URI-p53-SCD1</t> axis mediating TKIs resistance and administration of aramchol re-sensitizing liver cancer cells to TKIs.
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Fig. 9 | Model for <t>the</t> <t>URI-p53-SCD1</t> axis mediating TKIs resistance and administration of aramchol re-sensitizing liver cancer cells to TKIs.
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Fig. 9 | Model for <t>the</t> <t>URI-p53-SCD1</t> axis mediating TKIs resistance and administration of aramchol re-sensitizing liver cancer cells to TKIs.
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Fig. 9 | Model for <t>the</t> <t>URI-p53-SCD1</t> axis mediating TKIs resistance and administration of aramchol re-sensitizing liver cancer cells to TKIs.
Primary Antibody Against Rmp Uri, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Fig. 9 | Model for the URI-p53-SCD1 axis mediating TKIs resistance and administration of aramchol re-sensitizing liver cancer cells to TKIs.

Journal: Nature communications

Article Title: URI alleviates tyrosine kinase inhibitors-induced ferroptosis by reprogramming lipid metabolism in p53 wild-type liver cancers.

doi: 10.1038/s41467-023-41852-z

Figure Lengend Snippet: Fig. 9 | Model for the URI-p53-SCD1 axis mediating TKIs resistance and administration of aramchol re-sensitizing liver cancer cells to TKIs.

Article Snippet: Antibodies used are URI (1:1000, Proteintech, 11277-1-AP,), SREBP1 (1:200, Santa Cruz, sc-13551), SCD1 (1:1000, ABclonal, A16429), FASN (1:1000, ABclonal, A19050), FADS2 (1:1000, ABclonal, A10270), GPX4 (1:1000, ABclonal, A11243), GCLM (1:1000, ABclonal, A11444), GCLC (1:1000, ABclonal, A4499), SLC7A11 (1:1000, Proteintech, 26864-1-AP), ACSL4 (1:1000, Proteintech, 22401-1-AP), MDM2 (1:1000, ABclonal, A13327), Myc-Tag (1:1000, ABclonal, AE010), Flag-Tag (1:1000, ABclonal, AE005), His-Tag (1:1000, ABclonal, AE003), HA-Tag (1:1000, ABclonal, AE008), ACC (1:1000, CST, 3676), TRIM28 (1:1000, Proteintech, 15202-1-AP,), P53 (1:1000, Proteintech, 10442-1-AP), P21 (1:1000, Proteintech, 10355-1-AP), USP5 (1:1000, ABclonal, A4202), USP7 (1:1000, ABclonal, A13564), USP14 (1:1000, ABclonal, A19589), Actin (1:5000, Proteintech, 66009-1-ig), GAPDH (1:5000, ABclonal, AC001).

Techniques: